Tg(Acta1-DMD)1Ndl
Transgene Detail
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| Symbol: |
Tg(Acta1-DMD)1Ndl |
| Name: |
transgene insertion 1, Uri Nudel |
| MGI ID: |
MGI:2387970 |
| Transgene: |
Tg(Acta1-DMD)1Ndl Location: unknown
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| Alliance: |
Tg(Acta1-DMD)1Ndl page
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| Strain of Origin: |
(BALB/cJ x C57BL/6)F1
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Acta1-DMD)1Ndl expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
DMD (1756) |
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Mutation details: The entire coding region of human DMD plus 190 bp of the 3' untranslated region was used as the transgene. The rat Acta1 promoter, exon 1, intron 1, and part of exon 2, was used to drive transgene expression in skeletal muscle. Expression of the transgene was confirmed by Western blot analysis of skeletal muscle tissue.
(J:22142)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:22142 Greenberg DS, et al., Exogenous Dp71 restores the levels of dystrophin associated proteins but does not alleviate muscle damage in mdx mice [see comments]. Nat Genet. 1994 Dec;8(4):340-4 |
| All: |
2 reference(s) |
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Analysis Tools
