Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mixl1tm1.1Robb
Name:	Mix paired-like homeobox; targeted mutation 1.1, Lorraine Robb
MGI ID:	MGI:2387829
Synonyms:	Mixl1deltaneo
Gene:	Mixl1  Location: Chr1:180520608-180524599 bp, - strand  Genetic Position: Chr1, 84.46 cM
Alliance:	Mixl1tm1.1Robb page

Germline Transmission:	Earliest citation of germline transmission: J:77443
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Disruption caused by insertion of vector   Mutation details: The floxed neo cassette was excised from Mixl1tm1Robb via in vivo cre mediated recombination. The previously inserted GFP sequence remained in place of the coding region of exon 1. (J:77443)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mixl1 Mutation:	20 strains or lines available

Original:	J:77443 Hart AH, et al., Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development. 2002 Aug;129(15):3597-608
All:	2 reference(s)