Tg(Fabp4-cre/ERT2)1Ipc
Transgene Detail
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Symbol: |
Tg(Fabp4-cre/ERT2)1Ipc |
Name: |
transgene insertion 1, I Pierre Chambon |
MGI ID: |
MGI:2387425 |
Synonyms: |
aP2-CreERT2, aP2-Cre-ERT2, Tg(Fabp4-cre/Esr1)1Ipc |
Transgene: |
Tg(Fabp4-cre/ERT2)1Ipc Location: unknown
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Alliance: |
Tg(Fabp4-cre/ERT2)1Ipc page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Fabp4-cre/ERT2)1Ipc expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Fabp4 |
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Mutation details: The transgenic construct encodes a tamoxifen-inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand-binding domain. The adipocyte fatty acid-binding protein 4 promoter was used to drive expression in white and brown adipose tissue.
(J:66706)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Fabp4
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:66706 Imai T, et al., Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):224-8 |
All: |
19 reference(s) |
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