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Tg(Dct-cre)3510Bee
Transgene Detail
Summary
Symbol: Tg(Dct-cre)3510Bee
Name: transgene insertion 3510, Friedrich Beermann
MGI ID: MGI:2387120
Synonyms: Dct-Cre
Transgene: Tg(Dct-cre)3510Bee  Location: unknown  
Alliance: Tg(Dct-cre)3510Bee page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Dct-cre)3510Bee expression driven by 1 gene
 
Mutation detailsThis transgene expresses cre recombinase under the control of the dopachrome tautomerase promoter, active in pigment cells. Two lines (3469 and 3510) were crossed to reporter animals and analyzed further. Data for 3469 is shown in the original reference, but this line died out due to disease and line 3510 was continued. Only some line 3510 animals expressed the transgene sufficiently to allow detection of recombinase activity, and it was further determined that the line is a germ-line deleter strain. (J:79094)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dct (species not specified)
Summary of all recombinase alleles driven by Dct.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:79094 Guyonneau L, et al., Expression of cre recombinase in pigment cells. Pigment Cell Res. 2002 Aug;15(4):305-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory