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Smad1tm1Abr
Targeted Allele Detail
Summary
Symbol: Smad1tm1Abr
Name: SMAD family member 1; targeted mutation 1, Anita B Roberts
MGI ID: MGI:2386127
Synonyms: Smad1flox, Smad1fx, Smad1fx(exon2), Smadfl
Gene: Smad1  Location: Chr8:80065024-80126057 bp, - strand  Genetic Position: Chr8, 37.56 cM
Alliance: Smad1tm1Abr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75139
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 2 was flanked by an upstream floxed neo cassette and a downstream single loxP site. (J:75139)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 194 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Smad1 Mutation:  32 strains or lines available
References
Original:  J:75139 Huang S, et al., Conditional knockout of the Smad1 gene. Genesis. 2002 Feb;32(2):76-9
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory