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Gene Expression Data
Assay Details
Assay
Reference: J:63189 Lammert E, et al., Notch gene expression during pancreatic organogenesis. Mech Dev. 2000 Jun;94(1-2):199-203
Assay type: RNA in situ
MGI Accession ID: MGI:2385768
Gene symbol: Notch2
Gene name: notch 2
Probe: Notch2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1I: embryonic day 11.5 (more )
Note: Double labeled: blue/violet - Notch2; brown - Gcg (assay MGI:2385763).
Structure Level Pattern Image Note
TS19: pancreas primordium Present Regionally restricted 1I Expression in the ducts. Notch2 expressing cells do not co-express Glucagon.
Specimen 2B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dorsal pancreatic duct of pancreas body Present 2B
TS23: dorsal pancreatic duct of pancreas tail Present 2B
TS23: ventral pancreatic duct Present 2B
Specimen 2C: embryonic day 15.5 (more )
Note: Double labeled: blue/violet - Notch2; brown - Gcg (assay MGI:2385763).
Structure Level Pattern Image Note
TS23: dorsal pancreatic duct of pancreas body Present 2C Expression does not overlap with Glucagon.
TS23: dorsal pancreatic duct of pancreas tail Present 2C Expression does not overlap with Glucagon.
TS23: ventral pancreatic duct Present 2C Expression does not overlap with Glucagon.
Specimen 2D: embryonic day 15.5 (more )
Note: Double labeled: blue/violet - Notch2; brown - Ins1 (assay MGI:7481228) and Ins2 (assay MGI:7481227).
Structure Level Pattern Image Note
TS23: dorsal pancreatic duct of pancreas body Present 2D Expression does not overlap with Insulin.
TS23: dorsal pancreatic duct of pancreas tail Present 2D Expression does not overlap with Insulin.
TS23: ventral pancreatic duct Present 2D Expression does not overlap with Insulin.
Specimen 2E: embryonic day 15.5 (more )
Note: Double labeled: blue/violet - Notch2; brown - Amy (assay MGI:2385761).
Structure Level Pattern Image Note
TS23: dorsal pancreatic duct of pancreas body Present 2E Expression does not overlap with Amylase.
TS23: dorsal pancreatic duct of pancreas tail Present 2E Expression does not overlap with Amylase.
TS23: ventral pancreatic duct Present 2E Expression does not overlap with Amylase.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory