Srftm2.1Nor
Targeted Allele Detail
|
Symbol: |
Srftm2.1Nor |
Name: |
serum response factor; targeted mutation 2.1, Alfred Nordheim |
MGI ID: |
MGI:2385465 |
Synonyms: |
Srf-flex1, Srfflox, SrfloxP |
Gene: |
Srf Location: Chr17:46859255-46867101 bp, - strand Genetic Position: Chr17, 22.9 cM
|
Alliance: |
Srftm2.1Nor page
|
|
Curved spine and cyanosis in Srftm2.1Nor/Srftm2.1Nor Tg(Myog-cre)1Eno/0 mice
Show the 3 phenotype image(s) involving this allele.
|
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:75123
|
Parent Cell Line: |
E14.1 (ES Cell)
|
Strain of Origin: |
129P2/OlaHsd
|
|
Allele Type: |
|
Targeted (Conditional ready, No functional change) |
Mutation: |
|
Insertion
|
|
|
Mutation details: The floxed fragment of Srftm2Nor containing the neo casssette was excised by the ubiquitous expression of cre recombinase. Exon 1 was left intact along with single loxP sites in the 5' untranslated region of Exon 1 and intron 1.
(J:75123)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Srf Mutation: |
25 strains or lines available
|
|
Original: |
J:75123 Wiebel FF, et al., Generation of mice carrying conditional knockout alleles for the transcription factor SRF. Genesis. 2002 Feb;32(2):124-6 |
All: |
23 reference(s) |
|