Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hnf1atm1Ylee
Name:	HNF1 homeobox A; targeted mutation 1, Ying-Hue Lee
MGI ID:	MGI:2384427
Synonyms:	Tcf1-
Gene:	Hnf1a  Location: Chr5:115087039-115109121 bp, - strand  Genetic Position: Chr5, 55.99 cM, cytoband F
Alliance:	Hnf1atm1Ylee page

Germline Transmission:	Earliest citation of germline transmission: J:47008
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The coding region of exon 1 was flanked by a loxP site 40 bp downstream of the transcription start site and a loxP-PGK-neo cassette 80 bp into intron 1. (J:47008)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hnf1a Mutation:	29 strains or lines available

Original:	J:47008 Lee YH, et al., Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse. Mol Cell Biol. 1998 May;18(5):3059-68
All:	1 reference(s)