Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	G6pdxa-m2Neu
Name:	glucose-6-phosphate dehydrogenase X-linked; mutation 2, Neuherberg
MGI ID:	MGI:2183760
Gene:	G6pdx  Location: ChrX:73453089-73472486 bp, - strand  Genetic Position: ChrX, 38.0 cM, cytoband A2-A3
Alliance:	G6pdxa-m2Neu page

Strain of Origin:

(102/El x C3H/El)F1

Allele Type:    Radiation induced (Hypomorph) Mutation:    Intragenic deletion   Mutation details: This is a hypomorphic allele; in hemizygous males, heterozygous females, and homozygous females, the activity level in blood is ~33%, ~65%, and ~29% of normal, respectively. The mutation has been identified as the deletion of exon 6 (159 base pairs). (J:82809, J:89396)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any G6pdx Mutation:	7 strains or lines available

Original:	J:89396 Baader SL, et al., Purkinje cell lineage and the topographic organization of the cerebellar cortex: a view from X inactivation mosaics. Dev Biol. 1996 Mar 15;174(2):393-406
All:	4 reference(s)