Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgfr2tm2.1Lni
Name:	fibroblast growth factor receptor 2; targeted mutation 2.1, Peter Lonai
MGI ID:	MGI:2183527
Synonyms:	FGFR2b-, Fgfr2IIIb-
Gene:	Fgfr2  Location: Chr7:129764181-129868538 bp, - strand  Genetic Position: Chr7, 73.19 cM
Alliance:	Fgfr2tm2.1Lni page

Germline Transmission:	Earliest citation of germline transmission: J:77698
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Modified isoform(s)) Mutation:    Insertion   Mutation details: The targeted mutation is derived from Fgfr2tm2Lni by crossing to a cre-expressing line to remove the floxed neomycin cassette from intron 9. The engineered stop codon in exon 8 was left intact. (J:77698)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr2 Mutation:	87 strains or lines available

Original:	J:77698 Eswarakumar VP, et al., The IIIc alternative of Fgfr2 is a positive regulator of bone formation. Development. 2002 Aug 15;129(16):3783-93
All:	5 reference(s)