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Gene Expression Data
Assay Details
Assay
Reference: J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
Assay type: RNA in situ
MGI Accession ID: MGI:2183503
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4F wt: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: definitive endoderm Present Regionally restricted 4F wt Expression is anterior.

Specimen 4F delta600/-: embryonic day 7.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS11: definitive endoderm Weak Regionally restricted 4F delta600/- Expression is anterior.

Specimen 4G wt: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: gut endoderm Present Regionally restricted 4G wt Expression is present in the anterior foregut.
TS13: future prosencephalon Present Regionally restricted 4G wt The limit of expression is in the ventral forebrain.

Specimen 4H wt: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: gut endoderm Present Regionally restricted 4H wt Expression is present in the anterior foregut.
TS13: future prosencephalon Present Regionally restricted 4H wt The limit of expression is in the ventral forebrain.

Specimen 4G delta600/-: embryonic day 8.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Absent 4G delta600/-
TS13: gut endoderm Weak Regionally restricted 4G delta600/- The expression in the anterior foregut is greatly reduced.

Specimen 4H delta600/-: embryonic day 8.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Absent 4H delta600/-
TS13: gut endoderm Weak Regionally restricted 4H delta600/- The expression in the anterior foregut is greatly reduced.

Specimen Shh delta600/-: embryonic day 8.5; Nodaltm1.1Rob/Nodaltm2Rob (more )
Structure Level Pattern Image Note
TS13: gut endoderm Present Regionally restricted 4I Expression is confined to the posterior midline and the hidgut endoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory