Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Galtm1Wyn
Name:	galanin and GMAP prepropeptide; targeted mutation 1, David Wynick
MGI ID:	MGI:2183172
Synonyms:	galanin -, Gal KO, GALKO
Gene:	Gal  Location: Chr19:3459915-3464544 bp, - strand  Genetic Position: Chr19, 3.16 cM
Alliance:	Galtm1Wyn page

Germline Transmission:	Earliest citation of germline transmission: J:78046
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 through 5 were replaced with a neomycin selection cassette. Protein encoded by the targeted locus was undetected by radioimmunoassays of homozygous mutant brain and peripheral tissues. (J:78046)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Gal Mutation:	22 strains or lines available

Original:	J:78046 Wynick D, et al., Galanin regulates prolactin release and lactotroph proliferation. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12671-6
All:	27 reference(s)