Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ephb4tm1And
Name:	Eph receptor B4; targeted mutation 1, David J Anderson
MGI ID:	MGI:2183162
Synonyms:	EphB4taulacZ
Gene:	Ephb4  Location: Chr5:137348371-137372784 bp, + strand  Genetic Position: Chr5, 76.38 cM
Alliance:	Ephb4tm1And page

Germline Transmission:	Earliest citation of germline transmission: J:57908
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A tau-lacZ-PGK-neo cassette replaced exon 1 and was fused in frame to the translation start codon via homologous recombination. Homozygous mutant embryos were identified by PCR genotyping at E9.5. (J:57908)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	58 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ephb4 Mutation:	40 strains or lines available

Original:	J:57908 Gerety SS, et al., Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell. 1999 Sep;4(3):403-14
All:	27 reference(s)