Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Eomestm1Apr
Name:	eomesodermin; targeted mutation 1, Andreas P Russ
MGI ID:	MGI:2182814
Synonyms:	EoLacZ, Eomes-
Gene:	Eomes  Location: Chr9:118307259-118315176 bp, + strand  Genetic Position: Chr9, 70.21 cM, cytoband F3
Alliance:	Eomestm1Apr page

Germline Transmission:	Earliest citation of germline transmission: J:60897
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Portions of exon 2 and intron 2 were replaced with a cassette containing IRES-lacZ and neo. The expression pattern of the lacZ reporter transgene lagged that of the endogenous gene but was otherwise similar. (J:60897)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eomes Mutation:	41 strains or lines available

Original:	J:60897 Russ AP, et al., Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature. 2000 Mar 2;404(6773):95-9
All:	5 reference(s)