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Gene Expression Data
Assay Details
Assay
Reference: J:77124 Shinozaki K, et al., Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development. 2002 Jul;129(14):3479-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2182353
Gene symbol: L1cam
Gene name: L1 cell adhesion molecule
Antibody: anti-L1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 10J: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present Regionally restricted 10J The expressing axons originate in the diencephalon and invade the cortex from the ventrolateral region along the subplate.
TS25: diencephalon Present Regionally restricted 10J The expressing axons originate in the diencephalon and invade the cortex from the ventrolateral region along the subplate.

Specimen 10K: embryonic day 17.5; Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present Regionally restricted 10K The expression axons project into the cortical plate, but there are fewer axons than in wild-type embryos.
TS25: diencephalon Present Regionally restricted 10K The expression axons project into the cortical plate, but there are fewer axons than in wild-type embryos.

Specimen 10L: embryonic day 17.5; Emx1tm1Sia/Emx1tm1Sia, Emx2tm1Sia/Emx2tm1Sia (more )
Structure Level Pattern Image Note
TS25: central nervous system ganglion Present 10L The neurons originate in the diencephalon, but project incorrectly into the external capsule and the amygdala.
TS25: diencephalon Present 10L The neurons originate in the diencephalon, but project incorrectly into the external capsule and the amygdala.
TS25: cerebral cortex Absent 10L


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory