Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Kif3atm1Noh Name: kinesin family member 3A; targeted mutation 1, Nobutaka Hirokawa MGI ID: MGI:2181727 Synonyms: kif3A- Gene: Kif3a  Location: Chr11:53458206-53492794 bp, + strand  Genetic Position: Chr11, 31.97 cM, cytoband A5-B1 Alliance: Kif3atm1Noh page

Severe developmental abnormalities in Kif3atm1Noh/Kif3atm1Noh mice Show the 4 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:55332
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequences encoding the anterior half of the P loop were replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos lacked gene expression as demonstrated by Western blot analysis of whole E9.5 embryos. (J:55332)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kif3a Mutation:	31 strains or lines available

Original:	J:55332 Takeda S, et al., Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis. J Cell Biol. 1999 May 17;145(4):825-36
All:	3 reference(s)