Adcyap1r1tm1.1Gsc
Targeted Allele Detail
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| Symbol: |
Adcyap1r1tm1.1Gsc |
| Name: |
adenylate cyclase activating polypeptide 1 receptor 1; targeted mutation 1.1, Gunther Schutz |
| MGI ID: |
MGI:2180119 |
| Synonyms: |
PAC1- |
| Gene: |
Adcyap1r1 Location: Chr6:55428963-55478436 bp, + strand Genetic Position: Chr6, 27.38 cM, cytoband B3
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| Alliance: |
Adcyap1r1tm1.1Gsc page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:76715
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| Parent Cell Line: |
E14.1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: ES cells were transfected with a construct in which a LoxP site was inserted just upstream of exon 11 and a floxed neomycin-thymidine-kinase region inserted downstream. The transient expression of cre recombinase in ES cells resulted in the excision of the selection genes and exon 11, which encodes a portion of the transmembrane domain IV and is included in all known splice variants.
(J:76715)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Adcyap1r1 Mutation: |
34 strains or lines available
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| Original: |
J:76715 Otto C, et al., Impairment of mossy fiber long-term potentiation and associative learning in pituitary adenylate cyclase activating polypeptide type I receptor-deficient mice. J Neurosci. 2001 Aug 1;21(15):5520-7 |
| All: |
4 reference(s) |
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Analysis Tools
