Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Adam9tm1Bbl
Name:	ADAM metallopeptidase domain 9; targeted mutation 1, Carl Blobel
MGI ID:	MGI:2180096
Synonyms:	mdc9-
Gene:	Adam9  Location: Chr8:25439627-25506943 bp, - strand  Genetic Position: Chr8, 13.7 cM
Alliance:	Adam9tm1Bbl page

Germline Transmission:	Earliest citation of germline transmission: J:74655
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin resistance gene was inserted into the exon encoding amino acids 32 through 66. Protein expression was undetectable in lung and brain tissue isolated from homozygous mutants and in tissue from homozygous mutant embryos. (J:74655)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adam9 Mutation:	44 strains or lines available

Original:	J:74655 Weskamp G, et al., Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Mol Cell Biol. 2002 Mar;22(5):1537-44
All:	16 reference(s)