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Gene Expression Data
Assay Details
Assay
Reference: J:75946 Kanai-Azuma M, et al., Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002 May;129(10):2367-79
Assay type: RNA in situ
MGI Accession ID: MGI:2180048
Gene symbol: Afp
Gene name: alpha fetoprotein
Probe: AFP probe4
Probe preparation: Antisense RNA
Results
Specimen 6H +/+: embryonic day 8.5 (more )
Note: This embryo was at early neural plate stage.
Structure Level Pattern Image Note
TS12: extraembryonic visceral endoderm Present Regionally restricted 6H +/+
Specimen 6H -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Note: This embryo was at early neural plate stage.
Structure Level Pattern Image Note
TS12: extraembryonic visceral endoderm Present Regionally restricted 6H -/-
Specimen 6I +/-: embryonic day 8.5; Sox17tm1Ysk/Sox17+ (more )
Note: This embryo was at headfold stage.
Structure Level Pattern Image Note
TS12: extraembryonic visceral endoderm Present Regionally restricted 6I +/-
Specimen 6I -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Note: This embryo was at headfold stage.
Structure Level Pattern Image Note
TS12: extraembryonic visceral endoderm Present Regionally restricted 6I -/-
TS12: gut endoderm Present Regionally restricted 6I -/- Unlike in wild-type, expression in the mutant extends into the posterior and lateral regions of the embryonic gut.
Specimen 6J +/-: embryonic day 8.5; Sox17tm1Ysk/Sox17+ (more )
Note: This embryo was at headfold stage.
Structure Level Pattern Image Note
TS12: extraembryonic visceral endoderm Present Regionally restricted 6J +/-
Specimen 6J -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Note: This embryo was at headfold stage.
Structure Level Pattern Image Note
TS12: extraembryonic visceral endoderm Present Regionally restricted 6J -/-
TS12: gut endoderm Present Regionally restricted 6J -/- Unlike in wild-type, expression in the mutant extends into the posterior and lateral regions of the embryonic gut.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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