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Gene Expression Data
Assay Details
Assay
Reference: J:75946 Kanai-Azuma M, et al., Depletion of definitive gut endoderm in Sox17-null mutant mice. Development. 2002 May;129(10):2367-79
Assay type: RNA in situ
MGI Accession ID: MGI:2180040
Gene symbol: Ihh
Gene name: Indian hedgehog
Probe: Ihh cDNA1
Probe preparation: Antisense RNA
Results
Specimen 4Q +/-: embryonic day 8.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS12: embryo endoderm Present 4Q +/- Expression is present in the definitive endoderm.
TS12: extraembryonic visceral endoderm Present 4Q +/-
Specimen 4Q -/-: embryonic day 8.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS12: embryo endoderm Absent 4Q -/-
TS12: extraembryonic visceral endoderm Present 4Q -/- Expression is increased into the lateral region of the gut relative to that seen in wild-type.
Specimen 4R +/-: embryonic day 9.5; Sox17tm1Ysk/Sox17+ (more )
Structure Level Pattern Image Note
TS15: gut Present Regionally restricted 4R +/- Expression is present in the definitive endoderm.
TS15: extraembryonic component Present Regionally restricted 4R +/- Expression is present in the visceral endoderm.
Specimen 4R -/-: embryonic day 9.5; Sox17tm1Ysk/Sox17tm1Ysk (more )
Structure Level Pattern Image Note
TS15: extraembryonic component Present Regionally restricted 4R -/- Expression is present in the visceral endoderm.
TS15: hindgut Absent 4R -/- Expression is absent from the mid and hindgut epithelia.
TS15: midgut Absent 4R -/- Expression is absent from the mid and hindgut epithelia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory