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Gene Expression Data
Assay Details
Assay
Reference: J:75952 Davies K, et al., Disruption of mesodermal enhancers for Igf2 in the minute mutant. Development. 2002 Apr;129(7):1657-68
Assay type: RNA in situ
MGI Accession ID: MGI:2178269
Gene symbol: Igf2
Gene name: insulin-like growth factor 2
Probe: Igf2 cDNA8
Probe preparation: Antisense labelled with alkaline phosphatase RNA
Visualized with: Alkaline phosphatase
Results
Specimen Mntp embryo: embryonic day 13.5; Minute/Minute+ (more )
Note: The minute allele was inherited via paternal transmission.
Structure Level Pattern Image Note
TS21: embryo Present Regionally restricted 3C left
TS21: heart Absent 3C left
TS21: metanephros Absent 3C left
TS28: placenta Absent 3C left
TS21: medulla oblongata part of 4th ventricle choroid plexus Present 3C left
TS21: metencephalon part of 4th ventricle choroid plexus Present 3C left

Specimen Wild-type embryo: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Present Regionally restricted 3C right

Specimen Mntp organs: embryonic day 13.5; Minute/Minute+ (more )
Note: The minute allele was inherited via paternal transmission.
Structure Level Pattern Image Note
TS21: gut Present 3D left Authors report reduced expression in intestine, lung, tongue and intercostal muscle.
TS21: lung Present 3D left Authors report reduced expression in intestine, lung, tongue and intercostal muscle.
TS21: pectoral girdle and thoracic body wall muscle Present 3D left Authors report reduced expression in intestine, lung, tongue and intercostal muscle.
TS21: tongue Present 3D left Authors report reduced expression in intestine, lung, tongue and intercostal muscle.

Specimen Wild-type organs: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: gut Present 3D right
TS21: lung Present 3D right
TS21: pectoral girdle and thoracic body wall muscle Present 3D right
TS21: tongue Present 3D right

Specimen Mntp intestine: embryonic day 13.5; Minute/Minute+ (more )
Note: The minute allele was inherited via paternal transmission.
Structure Level Pattern Image Note
TS21: gut Present Regionally restricted 3E left Residual expression restricted to epithelial lining; absent in smooth muscle layer.

Specimen Wild-type intestine: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: gut Present 3E right Expression in epithelial lining and smooth muscle layer of intestine.

Specimen Mntp lung: embryonic day 13.5; Minute/Minute+ (more )
Note: The minute allele was inherited via paternal transmission.
Structure Level Pattern Image Note
TS21: lung Present Regionally restricted 3F left Expression in epithelial cells of bronchi with closed or small lumina; absent in open bronchi and mesenchyme.

Specimen Wild-type lung: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung Present 3F right Expression in bronchial epithelium and mesenchyme.

Specimen not shown (male): embryonic day 13.5; Minute/Minute+ (more )
Structure Level Pattern Image Note
TS21: dermis Absent
TS21: diaphragm Absent
TS21: genital tubercle of male Absent

Specimen not shown (female): embryonic day 13.5; Minute/Minute+ (more )
Structure Level Pattern Image Note
TS21: dermis Absent
TS21: diaphragm Absent
TS21: genital tubercle of female Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory