Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wnt2tm1Bjw
Name:	wingless-type MMTV integration site family, member 2; targeted mutation 1, Brandon J Wainwright
MGI ID:	MGI:2177935
Gene:	Wnt2  Location: Chr6:17988939-18030584 bp, - strand  Genetic Position: Chr6, 8.08 cM, cytoband A2-A3.1
Alliance:	Wnt2tm1Bjw page

Germline Transmission:	Earliest citation of germline transmission: J:36835
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin resistance cassette was inserted into exon 3. RT-PCR analysis in RNA derived from lung and heart demonstrated that aberrant trancripts were made from this allele, but none are expected to encode a functional protein. (J:36835)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt2 Mutation:	26 strains or lines available

Original:	J:36835 Monkley SJ, et al., Targeted disruption of the Wnt2 gene results in placentation defects. Development. 1996 Nov;122(11):3343-53
All:	3 reference(s)