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Gene Expression Data
Assay Details
Assay
Reference: J:73781 Kwang SJ, et al., Msx2 is an immediate downstream effector of Pax3 in the development of the murine cardiac neural crest. Development. 2002 Jan;129(2):527-38
Assay type: RNA in situ
MGI Accession ID: MGI:2177926
Gene symbol: Msx2
Gene name: msh homeobox 2
Probe: Msx2 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3B, E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 5 Strong 3B , 3E
TS15: future hindbrain Present Regionally restricted 3B , 3E Lower levels of expression caudal to rhombomere 5.

Specimen 3C, F: embryonic day 9.5; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 3C , 3F An increase of intensity of signal in the postotic hindbrain relative to the otic region.

Specimen 3H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 5 roof plate Present 3H
TS15: future hindbrain Present Regionally restricted 3H At the level of the otic vesicle, expression in the dorsal neural tube.

Specimen 3I: embryonic day 9.5; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 3I The expression domain has expanded compared to wild-type embryos.

Specimen 3K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 6 Present Regionally restricted 3K In the postotic neural tube the expression is in a medial to lateral gradient.
TS15: rhombomere 7 Present Regionally restricted 3K In the postotic neural tube the expression is in a medial to lateral gradient.
TS15: rhombomere 8 Present Regionally restricted 3K In the postotic neural tube the expression is in a medial to lateral gradient.
TS15: future hindbrain Weak Regionally restricted 3K In the mid-dorsal region of the neural tube.

Specimen 3L: embryonic day 9.5; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 3L In the postotic hindbrain, expression expanded into the dorsal and lateral regions of the neural tube.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory