Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Evx1tm1Mrc
Name:	even-skipped homeobox 1; targeted mutation 1, Mario R Capecchi
MGI ID:	MGI:2177782
Synonyms:	evx1-
Gene:	Evx1  Location: Chr6:52290483-52295363 bp, + strand  Genetic Position: Chr6, 25.44 cM
Alliance:	Evx1tm1Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:20014
Parent Cell Line:	CC1.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced a DNA segment coding for the first amino acid residues of the first helix of the homeobox domain and part of intron 2. (J:20014)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Evx1 Mutation:	18 strains or lines available

Original:	J:20014 Spyropoulos DD, et al., Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. Genes Dev. 1994 Aug 15;8(16):1949-61
All:	2 reference(s)