Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Erbb2tm2.1Cbm
Name:	erb-b2 receptor tyrosine kinase 2; targeted mutation 2.1, Carmen Birchmeier
MGI ID:	MGI:2177256
Synonyms:	Erbb2delta
Gene:	Erbb2  Location: Chr11:98303310-98328542 bp, + strand  Genetic Position: Chr11, 61.75 cM, cytoband D
Alliance:	Erbb2tm2.1Cbm page

Germline Transmission:	Earliest citation of germline transmission: J:75421
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Erbb2tm2Cbr in which the loxP flanked sequences were deleted in vivo by crossing mice carrying this allele to mice carrying the TgN(CMV-Cre)1Cgn transgene. (J:75421)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Erbb2 Mutation:	59 strains or lines available

Original:	J:75421 Garratt AN, et al., A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool. J Cell Biol. 2000 Mar 6;148(5):1035-46
All:	2 reference(s)