Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Arnttm1Gonz
Name:	aryl hydrocarbon receptor nuclear translocator; targeted mutation 1, Frank Gonzalez
MGI ID:	MGI:2176696
Synonyms:	Arntflox, ARNT flox, Arnt-floxed, Arntflox(neo), Hif-1betafl
Gene:	Arnt  Location: Chr3:95341699-95404551 bp, + strand  Genetic Position: Chr3, 40.74 cM
Alliance:	Arnttm1Gonz page

Germline Transmission:	Earliest citation of germline transmission: J:64967
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP flanked neomycin resistance cassette was inserted 5' to exon 6 and a single loxP site was inserted 3' to exon 6. (J:64967)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arnt Mutation:	62 strains or lines available

Original:	J:64967 Tomita S, et al., Conditional disruption of the aryl hydrocarbon receptor nuclear translocator (Arnt) gene leads to loss of target gene induction by the aryl hydrocarbon receptor and hypoxia-inducible factor 1alpha. Mol Endocrinol. 2000 Oct;14(10):1674-81
All:	31 reference(s)