Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Atrtm1Bal
Name:	ataxia telangiectasia and Rad3 related; targeted mutation 1, David Baltimore
MGI ID:	MGI:2176600
Synonyms:	ATR-
Gene:	Atr  Location: Chr9:95739650-95833834 bp, + strand  Genetic Position: Chr9, 50.27 cM, cytoband E4
Alliance:	Atrtm1Bal page

Germline Transmission:	Earliest citation of germline transmission: J:60768
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129S/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic fragment containing the first three exons was replaced with a neomycin resistance cassette. (J:60768)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

16 anatomical structure(s)

List all tumor models in MMHCdb carrying Atrtm1Bal

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atr Mutation:	132 strains or lines available

Original:	J:60768 Brown EJ, et al., ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev. 2000 Feb 15;14(4):397-402
All:	13 reference(s)