Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	AatfGt(pGT1.8geo)3Pgr
Name:	apoptosis antagonizing transcription factor; gene trap 3, Peter Gruss
MGI ID:	MGI:2176283
Synonyms:	Trbgt
Gene:	Aatf  Location: Chr11:84313681-84404348 bp, - strand  Genetic Position: Chr11, 51.3 cM, cytoband B5
Alliance:	AatfGt(pGT1.8geo)3Pgr page

Germline Transmission:	Earliest citation of germline transmission: J:65741
Parent Cell Line:	MPI-II (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: Identified in a screen for genes important in embryonic development. The gene trap insertion created in a fusion between the first 245 amino acids and the construct. The resultant fusion protein did not retain any function of the endogenous gene and did not display any obvious dominant negative effects. (J:65741)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	31 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aatf Mutation:	40 strains or lines available

Original:	J:65741 Thomas T, et al., The murine gene, traube, is essential for the growth of preimplantation embryos. Dev Biol. 2000 Nov 15;227(2):324-42
All:	2 reference(s)