Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Tg(MMTV-cre)4Mam
Name:	transgene insertion 4, Lothar Hennighausen
MGI ID:	MGI:2176166
Synonyms:	CreD, D-line, Line D, MMTV-Cre, MMTV-CreD, MMTV-CreD
Transgene:	Tg(MMTV-cre)4Mam  Location: unknown
Alliance:	Tg(MMTV-cre)4Mam page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(MMTV-cre)4Mam expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note virus MMTV   Mutation details: This transgene directs the expression of Cre recombinase under the control of the mouse mammary tumor virus (MMTV) long terminal repeat. The viral MMTV promoter directed expression of Cre recombinase in the secretory epithelium of the mammary gland, the salivary gland, seminal vesicle, skin, erythrocytes, B and T cells. This line does not express cre in oocytes. (J:67925, J:74366)

Activity:	Tissue activity of this recombinase allele
Driver:	MMTV (virus) Summary of all recombinase alleles driven by MMTV.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(MMTV-cre)4Mam

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:67925 Wagner KU, et al., Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res. 1997 Nov 1;25(21):4323-30
All:	160 reference(s)