Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Arfrp1tm1Asch
Name:	ADP-ribosylation factor related protein 1; targeted mutation 1, A Schurmann
MGI ID:	MGI:2159671
Gene:	Arfrp1  Location: Chr2:180999483-181007197 bp, - strand  Genetic Position: Chr2, 103.63 cM
Alliance:	Arfrp1tm1Asch page

Germline Transmission:	Earliest citation of germline transmission: J:74645
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2 and 3, containing the start codon, the PM1-PM3 motifs, and the G1 motif, were replaced with a neomycin resistance cassette. (J:74645)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arfrp1 Mutation:	19 strains or lines available

Original:	J:74645 Mueller AG, et al., Embryonic Lethality Caused by Apoptosis during Gastrulation in Mice Lacking the Gene of the ADP-Ribosylation Factor-Related Protein 1. Mol Cell Biol. 2002 Mar;22(5):1488-94
All:	3 reference(s)