Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Cln6nclf
Name:	ceroid-lipofuscinosis, neuronal 6; neuronal ceroid lipofuscinosis
MGI ID:	MGI:2159328
Synonyms:	nclf
Gene:	Cln6  Location: Chr9:62746067-62759288 bp, + strand  Genetic Position: Chr9, 33.89 cM
Alliance:	Cln6nclf page

Strain of Origin:

Mixed stock

Allele Type:    Spontaneous Mutation:    Insertion   Mutation details: This allele comprises a single nucleotide insertion of a cysteine, located within a run of cysteines in exon four. The insertion produces a frameshift at amino acid 103, followed by a premature stop codon. (J:73921, J:73923) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cln6 Mutation:	33 strains or lines available

Original:	J:47292 Bronson RT, et al., Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9. Am J Med Genet. 1998 May 26;77(4):289-97
All:	21 reference(s)