Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Sema3atm1.1Tyag
Name:	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; targeted mutation 1.1, Takeshi Yagi
MGI ID:	MGI:2158944
Synonyms:	Sema3a-, semaphorin III/D null
Gene:	Sema3a  Location: Chr5:13175381-13652533 bp, + strand  Genetic Position: Chr5, 4.31 cM
Alliance:	Sema3atm1.1Tyag page

Germline Transmission:	Earliest citation of germline transmission: J:43443
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: This allele was generated from Sema3atm1Tyag by transient cre expression in TT-2 cells. Recombination produced three alleles, Sema3atm1.1Tyag, Sema3atm1.2Tyag and Sema3atm1.3Tyag. Sema3tm1.1Tyag has had the first exon, including the initiation codon, deleted. (J:43443) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	49 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sema3a Mutation:	47 strains or lines available

Original:	J:43443 Taniguchi M, et al., Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron. 1997 Sep;19(3):519-30
All:	45 reference(s)