Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Npy1rtm1Aka
Name:	neuropeptide Y receptor Y1; targeted mutation 1, Akio Kanatani
MGI ID:	MGI:2158689
Gene:	Npy1r  Location: Chr8:67149844-67159444 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Alliance:	Npy1rtm1Aka page

Germline Transmission:	Earliest citation of germline transmission: J:60632
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The gene was disrupted using neomycin resistance cassette. The vector replaced both exons 1 and 2. Northern analysis failed to detect transcript in homozygous mutant animals. (J:60632)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:	25 strains or lines available

Original:	J:60632 Kanatani A, et al., Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice. Endocrinology. 2000 Mar;141(3):1011-6
All:	1 reference(s)