Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mafbm1Gsb
Name:	MAF bZIP transcription factor B; mutation 1, Gregory S Barsh
MGI ID:	MGI:2157803
Synonyms:	kreislerenu, krENU, MafBENU
Gene:	Mafb  Location: Chr2:160205623-160208985 bp, - strand  Genetic Position: Chr2, 80.92 cM
Alliance:	Mafbm1Gsb page

Strain of Origin:

(BALB/cJ x SJL/J)F1

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: An A-to-G transition at nucleotide 743 resulted in an asparagine to serine substitution at amino acid 248. The mutation is in the putative DNA-binding domain and is conserved among other gene family members. (J:22020) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

27 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mafb Mutation:	18 strains or lines available

Original:	J:22020 Cordes SP, et al., The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 1994 Dec 16;79(6):1025-34
All:	5 reference(s)