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Gene Expression Data
Assay Details
Assay
Reference: J:43309 Meyer D, et al., Isoform-specific expression and function of neuregulin. Development. 1997 Sep;124(18):3575-86
Assay type: RNA in situ
MGI Accession ID: MGI:2155250
Gene symbol: Erbb3
Gene name: erb-b2 receptor tyrosine kinase 3
Probe: ErbB3 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4P: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: dorsal root ganglion Strong 4P
TS16: peripheral nervous system Strong Regionally restricted 4P Expression in cells that line all developing axons in the periphery.
TS16: trunk mesenchyme Strong Regionally restricted 4P Expression in skeletal muscle.

Specimen 4Q: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Strong 4Q
TS20: peripheral nervous system Strong Regionally restricted 4Q Expression in cells that line all developing axons in the periphery.
TS20: trunk mesenchyme Strong Regionally restricted 4Q Expression in skeletal muscle.

Specimen 4R: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Strong 4R
TS26: peripheral nervous system Strong 4R Expression in cells that line all developing axons in the periphery.
TS26: vertebral axis musculature Strong 4R Expression in skeletal muscle.

Specimen 7F: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: thalamus Present Regionally restricted 7F Expression in the nuclei of the thalamus.
TS26: olfactory epithelium Strong 7F

Specimen Table 1: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Absent
TS20: cerebral cortex Absent
TS20: telencephalon Absent Absent in the olfactory lobes.
TS20: diencephalon Absent
TS20: midbrain Absent
TS20: medulla oblongata Absent
TS20: pons Absent
TS20: spinal cord Absent
TS20: nasal cavity epithelium Strong Expression was strong in the undifferentiated epithelium.
TS20: retina Absent Absent in the undifferentiated epithelium.
TS20: inner ear epithelium Absent Absent in the undifferentiated epithelium.
TS20: sympathetic ganglion Present
TS20: skeletal muscle Strong
TS20: cardiac muscle tissue Absent
TS20: atrioventricular endocardial cushion Strong
TS20: endocardial cushion Strong
TS20: right atrium valve Strong
TS20: endocardial lining Absent

Specimen Table 1: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Absent
TS23: cerebral cortex Absent
TS23: olfactory lobe Absent
TS23: corpus striatum Absent
TS23: diencephalon Absent
TS23: midbrain Absent
TS23: medulla oblongata Absent
TS23: pons Absent
TS23: spinal cord Absent
TS23: choroid plexus Absent
TS23: pituitary gland Present
TS23: nasal cavity respiratory epithelium Strong
TS23: olfactory epithelium Strong
TS23: retina nuclear layer Absent Absent in the nuclear and ganglion cell layer.
TS23: inner ear epithelium Present Expression was detected in the sensory and non-sensory epithelium.
TS23: sympathetic ganglion Present
TS23: skeletal muscle Strong
TS23: cardiac muscle tissue Absent
TS23: atrioventricular endocardial cushion Present
TS23: bulbar cushion Present
TS23: endocardial cushion Present
TS23: heart valve Present
TS23: endocardial tissue Absent

Specimen Table 1: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Absent
TS26: cerebral cortex Absent
TS26: hippocampus Absent
TS26: olfactory lobe Present
TS26: corpus striatum Absent
TS26: telencephalon Present Regionally restricted Expression was detected in the olfactory lobes but was absent in the claustrum.
TS26: diencephalon Present
TS26: midbrain Present
TS26: cerebellum Absent Expression was absent in the cortex and medulla.
TS26: medulla oblongata Absent
TS26: pons Absent
TS26: spinal cord Absent
TS26: choroid plexus Absent
TS26: pituitary gland Absent
TS26: nasal cavity respiratory epithelium Strong
TS26: olfactory epithelium Strong
TS26: retina nuclear layer Absent Expression was absent from the nuclear and ganglion cell layers.
TS26: inner ear epithelium Present Regionally restricted Expression was detected in the sensory and non-sensory epithelium.
TS26: sympathetic ganglion Present
TS26: skeletal muscle Present
TS26: cardiac muscle tissue Absent
TS26: atrioventricular endocardial cushion Present
TS26: endocardial cushion Present
TS26: heart valve Present
TS26: endocardial tissue Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory