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Gene Expression Data
Assay Details
Assay
Reference: J:43309 Meyer D, et al., Isoform-specific expression and function of neuregulin. Development. 1997 Sep;124(18):3575-86
Assay type: RNA in situ
MGI Accession ID: MGI:2155248
Gene symbol: Erbb4
Gene name: erb-b2 receptor tyrosine kinase 4
Probe: ErbB4 cDNA3
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4M: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: future spinal cord Present Regionally restricted 4M Expression in two stripes of cells in the spinal cord.

Specimen 4N: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: spinal cord Strong Regionally restricted 4N Expression in the ventral portion.
TS20: trunk mesenchyme Weak Regionally restricted 4N Expression in skeletal muscles.

Specimen 4O: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: spinal cord Present Uniform 4O

Specimen 7E: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: brain Strong 7E
TS26: telencephalon Strong Regionally restricted 7E Expression in the cortical plate, ventricular zone and claustrum.
TS26: cortical plate Strong 7E
TS26: midbrain Strong Regionally restricted 7E Expression in various nuclei.

Specimen Table 1: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Absent
TS20: cerebral cortex Strong
TS20: telencephalon Strong Regionally restricted Expression in the olfactory lobes.
TS20: diencephalon Strong
TS20: midbrain Strong
TS20: medulla oblongata Strong
TS20: pons Strong
TS20: spinal cord Strong
TS20: nasal cavity epithelium Absent Absent in the undifferentiated epithelium.
TS20: retina Absent Absent in the undifferentiated epithelium.
TS20: inner ear epithelium Present Present in the undifferentiated epithelium.
TS20: sympathetic ganglion Absent
TS20: skeletal muscle Present
TS20: cardiac muscle tissue Strong
TS20: atrioventricular endocardial cushion Absent
TS20: endocardial cushion Absent
TS20: right atrium valve Absent
TS20: endocardial lining Absent

Specimen Table 1: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Absent
TS23: cerebral cortex Strong
TS23: olfactory lobe Strong
TS23: corpus striatum Strong
TS23: diencephalon Strong
TS23: midbrain Strong
TS23: medulla oblongata Strong
TS23: pons Strong
TS23: spinal cord Strong
TS23: choroid plexus Absent
TS23: pituitary gland Present
TS23: nasal cavity respiratory epithelium Absent
TS23: olfactory epithelium Absent
TS23: retina nuclear layer Absent Absent in the nuclear and ganglion cell layers.
TS23: inner ear epithelium Absent Absent in the sensory and non-sensory epithelium.
TS23: sympathetic ganglion Absent
TS23: skeletal muscle Present
TS23: cardiac muscle tissue Strong
TS23: atrioventricular endocardial cushion Present
TS23: bulbar cushion Present
TS23: endocardial cushion Present
TS23: heart valve Present
TS23: endocardial tissue Absent

Specimen Table 1: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Strong
TS26: cerebral cortex Strong
TS26: hippocampus Strong
TS26: olfactory lobe Strong
TS26: corpus striatum Present
TS26: telencephalon Strong Regionally restricted Expression was detected in the claustrum.
TS26: diencephalon Strong
TS26: midbrain Strong
TS26: cerebellum Strong Regionally restricted Expression was detected in the cortex and the medulla.
TS26: medulla oblongata Strong
TS26: pons Strong
TS26: spinal cord Strong
TS26: choroid plexus Absent
TS26: pituitary gland Strong
TS26: nasal cavity respiratory epithelium Absent
TS26: olfactory epithelium Absent
TS26: retina nuclear layer Present Regionally restricted Expression was detected in the ganglion cell layer but was absent from the other nuclear layers.
TS26: inner ear Present Regionally restricted Expression was detected in sensory epithelium but was absent in non-sensory epithelium.
TS26: sympathetic ganglion Absent
TS26: skeletal muscle Weak
TS26: cardiac muscle tissue Strong
TS26: atrioventricular endocardial cushion Strong
TS26: endocardial cushion Strong
TS26: heart valve Strong
TS26: endocardial tissue Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory