About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:43309 Meyer D, et al., Isoform-specific expression and function of neuregulin. Development. 1997 Sep;124(18):3575-86
Assay type: RNA in situ
MGI Accession ID: MGI:2155246
Gene symbol: Nrg1
Gene name: neuregulin 1
Probe: neuregulin type II
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4G: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: notochord Present 4G

Specimen 4H: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 4H
TS20: spinal cord Present 4H
TS20: trunk mesenchyme Weak Regionally restricted 4H Expression in the skeletal muscles.

Specimen 4I: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: dorsal root ganglion Present 4I
TS26: spinal cord Present 4I
TS26: vertebral axis musculature Weak 4I Expression in the skeletal muscles.

Specimen 7C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: brain Weak Uniform 7C Expression at low levels in all parts of the brain.
TS26: cerebral cortex ventricular zone Strong 7C
TS26: telencephalon Strong Regionally restricted 7C Expression in the claustrum.
TS26: retina Strong 7C

Specimen Table 1: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Strong
TS20: cerebral cortex Present
TS20: telencephalon Present Regionally restricted Expression in the olfactory lobes.
TS20: diencephalon Present
TS20: midbrain Present
TS20: medulla oblongata Present
TS20: pons Present
TS20: spinal cord Present
TS20: nasal cavity epithelium Absent Absent in undifferentiated epithelium.
TS20: retina Absent Absent in undifferentiated epithelium.
TS20: inner ear epithelium Absent Absent in undifferentiated epithelium.
TS20: sympathetic ganglion Absent
TS20: skeletal muscle Present
TS20: cardiac muscle tissue Absent
TS20: atrioventricular endocardial cushion Absent
TS20: endocardial cushion Absent
TS20: right atrium valve Absent
TS20: endocardial lining Absent

Specimen Table 1: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Strong
TS23: cerebral cortex Present
TS23: olfactory lobe Present
TS23: corpus striatum Present
TS23: diencephalon Present
TS23: midbrain Present
TS23: medulla oblongata Present
TS23: pons Present
TS23: spinal cord Strong
TS23: choroid plexus Absent
TS23: pituitary gland Strong
TS23: olfactory epithelium Absent
TS23: nasal cavity respiratory epithelium Absent
TS23: retina nuclear layer Absent Expression was absent from the nuclear and ganglion cell layers.
TS23: inner ear epithelium Absent Absent in the sensory and non-sensory epithelium.
TS23: sympathetic ganglion Absent
TS23: skeletal muscle Present
TS23: cardiac muscle tissue Absent
TS23: atrioventricular endocardial cushion Absent
TS23: bulbar cushion Absent
TS23: endocardial cushion Absent
TS23: heart valve Absent
TS23: endocardial tissue Absent

Specimen Table 1: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular zone Strong
TS26: cerebral cortex Present
TS26: hippocampus Absent
TS26: olfactory lobe Present
TS26: corpus striatum Strong
TS26: telencephalon Strong Regionally restricted Expression in the claustrum.
TS26: diencephalon Strong
TS26: midbrain Strong
TS26: cerebellum Present Regionally restricted Expression was detected in the medulla but was absent from the cortex.
TS26: medulla oblongata Present
TS26: pons Present
TS26: spinal cord Strong
TS26: choroid plexus Absent
TS26: pituitary gland Strong
TS26: nasal cavity respiratory epithelium Absent
TS26: olfactory epithelium Absent
TS26: retina nuclear layer Present Regionally restricted Expression was detected in the ganglion cell layer but was absent from the other nuclear layers.
TS26: inner ear epithelium Absent Absent in sensory and non-sensory epithelium.
TS26: sympathetic ganglion Absent
TS26: skeletal muscle Present
TS26: cardiac muscle tissue Absent
TS26: atrioventricular endocardial cushion Absent
TS26: endocardial cushion Absent
TS26: heart valve Absent
TS26: endocardial tissue Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory