Gene Expression Data
Assay Details
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Assay
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Reference:
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J:72724
Toresson H, et al., A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:2154698
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Gene symbol:
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Sox1
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Gene name:
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SRY (sex determining region Y)-box 1
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Antibody:
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Anti-SOX1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
1C:
embryonic day 18.5
(more  )
Specimen
1C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Uniform |
1C
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Expression is restricted to the olfactory tubercle and the nucleus accumbens.
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Specimen
1D:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Regionally restricted |
1D
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There is a reduction in the area of expression. The reduction is less affected in the nucleus accumbens than in the olfactory tubercle.
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Specimen
5C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Gsx1tm1Ssp/Gsx1tm1Ssp
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Present |
Regionally restricted |
5C
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Expression is restricted to the olfactory tubercle and the nucleus accumbens. Expression in this mutant is the same as in wild-type embryos.
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Specimen
5D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * 129S2/SvPas
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Mutant Allele(s):
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Gsx1tm1Ssp/Gsx1tm1Ssp
Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: telencephalon |
Trace |
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5D
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This mutant has a rudimentary striatum and expression is almost absent.
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Analysis Tools
