Summary | Mutation origin | Mutation description | Tumor data | Find Mice (IMSR) | References

Symbol:	Junbtm1Wag
Name:	jun B proto-oncogene; targeted mutation 1, Erwin F Wagner
MGI ID:	MGI:2153821
Synonyms:	junB-
Gene:	Junb  Location: Chr8:85703538-85705377 bp, - strand  Genetic Position: Chr8, 41.41 cM, cytoband C2-D1
Alliance:	Junbtm1Wag page

Germline Transmission:	Earliest citation of germline transmission: J:53304
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 486 bp fragment encoding the DNA binding and protein dimerization domains was replaced with a promoterless neomycin resistance gene. The resulting mutation fused the first 220 codons to the fifth codon of the neomycin gene. (J:53304)

List all tumor models in MMHCdb carrying Junbtm1Wag

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Junb Mutation:	19 strains or lines available

Original:	J:53304 Schorpp-Kistner M, et al., JunB is essential for mammalian placentation. EMBO J. 1999 Feb 15;18(4):934-48
All:	9 reference(s)