Hoxd13 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:71694 Bruneau S, et al., The mouse hoxd13(spdh) mutation, a polyalanine expansion similar to human type ii synpolydactyly (spd), disrupts the function but not the expression of other hoxd genes. Dev Biol. 2001 Sep 15;237(2):345-53
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:2153106
Gene symbol:	Hoxd13
Gene name:	homeobox D13

Antibody:

anti-HoxD13

Results

3F wt ©

Specimen 3F, wt: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: footplate	Present	Regionally restricted	3F wt	Expression in the distal region of the autopods.
TS19: handplate	Present	Regionally restricted	3F wt	Expression in the distal region of the autopods.
TS19: footplate ectoderm	Absent		3F wt
TS19: handplate ectoderm	Absent		3F wt

3F spdh/spdh ©

Specimen 3F, -/-: embryonic day 11.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS19: footplate	Present	Regionally restricted	3F spdh/spdh	Expression in the distal region of the autopods was the same as in wild-type embryos.
TS19: handplate	Present	Regionally restricted	3F spdh/spdh	Expression in the distal region of the autopods was the same as in wild-type embryos.
TS19: footplate ectoderm	Absent		3F spdh/spdh
TS19: handplate ectoderm	Absent		3F spdh/spdh

3G wt top ©

Specimen 3G, wt, top: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: handplate	Present	Regionally restricted	3G wt top	Expression in the distal region of the autopods.
TS19: handplate ectoderm	Absent		3G wt top

3G wt bottom ©

Specimen 3G, wt, bottom: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: footplate	Present	Regionally restricted	3G wt bottom	Expression in the distal region of the autopods.
TS19: footplate ectoderm	Absent		3G wt bottom

3G spdh/spdh top ©

Specimen 3G, -/-, top: embryonic day 11.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS19: handplate	Present	Regionally restricted	3G spdh/spdh top	Expression in the distal region of the autopods was the same as in wild-type embryos.
TS19: handplate ectoderm	Absent		3G spdh/spdh top

3G spdh/spdh bottom ©

Specimen 3G, -/-, bottom: embryonic day 11.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS19: footplate	Present	Regionally restricted	3G spdh/spdh bottom	Expression in the distal region of the autopods was the same as in wild-type embryos.
TS19: footplate ectoderm	Absent		3G spdh/spdh bottom

3H wt top ©

Specimen 3H, wt, top: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: hand	Present	Regionally restricted	3H wt top	Expression in the distal region of the autopods.
TS20: hand epithelium	Absent		3H wt top	Absence of expression in the ectoderm overlying the autopod.

3H wt bottom ©

Specimen 3H, wt, bottom: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: foot	Present	Regionally restricted	3H wt bottom	Expression in the distal region of the autopods.
TS20: foot epithelium	Absent		3H wt bottom	Absence of expression in the ectoderm overlying the autopod.

Specimen 3H, -/+, top: embryonic day 12.5; Hoxd13^spdh/Hoxd13⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: hand	Present	Regionally restricted	3H spdh/+ top	Expression in the distal region of the autopods.
TS20: hand epithelium	Absent		3H spdh/+ top	Absence of expression in the ectoderm overlying the autopod.

Specimen 3H, -/+, bottom: embryonic day 12.5; Hoxd13^spdh/Hoxd13⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: foot	Present	Regionally restricted	3H spdh/+ bottom	Expression in the distal region of the autopods.
TS20: foot epithelium	Absent		3H spdh/+ bottom	Absence of expression in the ectoderm overlying the autopod.

Specimen 3H, -/-, top: embryonic day 12.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS20: hand	Moderate	Regionally restricted	3H spdh/spdh top	Expression in the distal region of the autopods.
TS20: hand epithelium	Absent		3H spdh/spdh top	Absence of expression in the ectoderm overlying the autopod.

Specimen 3H, -/-, bottom: embryonic day 12.5; Hoxd13^spdh/Hoxd13^spdh (more

)

Structure	Level	Pattern	Image	Note
TS20: foot	Moderate	Regionally restricted	3H spdh/spdh bottom	Expression in the distal region of the autopods.
TS20: foot epithelium	Absent		3H spdh/spdh bottom	Absence of expression in the ectoderm overlying the autopod.

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