Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Taf4btm1Rtj
Name:	TATA-box binding protein associated factor 4b; targeted mutation 1, Robert Tjian
MGI ID:	MGI:2152347
Synonyms:	TAF4B-, TAFII105
Gene:	Taf4b  Location: Chr18:14916302-15033416 bp, + strand  Genetic Position: Chr18, 8.28 cM
Alliance:	Taf4btm1Rtj page

Germline Transmission:	Earliest citation of germline transmission: J:71679
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Half of exon "h" located in the 3' end of the gene was replaced with a neomycin cassette inserted in reverse transcriptional orientation to the gene. Western blot analysis of B cell extracts derived from mice of each genotype confirmed that the protein was not expressed in homozygous mice.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Taf4b Mutation:	50 strains or lines available

Original:	J:71679 Freiman RN, et al., Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science. 2001 Sep 14;293(5537):2084-7
All:	11 reference(s)