Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb3tm1Mrc
Name:	homeobox B3; targeted mutation 1, Mario R Capecchi
MGI ID:	MGI:2151773
Synonyms:	Hoxb3-
Gene:	Hoxb3  Location: Chr11:96214152-96238756 bp, + strand  Genetic Position: Chr11, 59.84 cM
Alliance:	Hoxb3tm1Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:45337
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 225 bp fragment of the gene encoding the entire homeobox domain was replaced with a neomycin cassette. (J:45337)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb3 Mutation:	16 strains or lines available

Original:	J:45337 Manley NR, et al., Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol. 1997 Dec 15;192(2):274-88
All:	7 reference(s)