Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb2tm1Mrc
Name:	homeobox B2; targeted mutation 1, Mario R Capecchi
MGI ID:	MGI:2151772
Synonyms:	hoxb-2-
Gene:	Hoxb2  Location: Chr11:96242458-96244846 bp, + strand  Genetic Position: Chr11, 59.85 cM
Alliance:	Hoxb2tm1Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:37682
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin cassette was inserted into the sequences encoding the homeobox domain in exon 2. (J:37682)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb2 Mutation:	12 strains or lines available

Original:	J:37682 Barrow JR, et al., Targeted disruption of the Hoxb-2 locus in mice interferes with expression of Hoxb-1 and Hoxb-4. Development. 1996 Dec;122(12):3817-28
All:	2 reference(s)