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Gene Expression Data
Assay Details
Assay
Reference: J:52602 Hunter PJ, et al., Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development. Development. 1999 Mar;126(6):1247-58
Assay type: RNA in situ
MGI Accession ID: MGI:2151198
Gene symbol: Dnajb6
Gene name: DnaJ heat shock protein family (Hsp40) member B6
Probe: pE3
Probe preparation: Antisense labelled with P32 RNA
Visualized with: Autoradiography
Results
Specimen 1E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: embryo Weak 1E Authors report low levels throughout most of embryo.
TS25: dorsal root ganglion Strong 1E
TS25: thymus Strong 1E
Specimen 1F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: embryo Present 1F Authors report low levels throughout most of embryo.
TS23: neural retina Present Regionally restricted 1F Expression in the ganglion neural layer of the retina.
Specimen 1H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: embryo Weak 1H Authors report low levels throughout most of embryo.
TS23: brain Present 1H
TS23: diencephalon Present 1H Consistently higher in expression in these structures.
TS23: midbrain Present 1H Consistently higher in expression in these structures.
TS23: trigeminal ganglion Present 1H Consistently higher in expression in these structures.
TS23: nasal cavity epithelium Present 1H
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: testis Present
Specimen 3G: embryonic day 8.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Note: Fixed in 4% paraformaldehyde, 0.02% glutaraldehyde.
Structure Level Pattern Image Note
TS13: chorion Present Non-Uniform 3G Expression is present in the trophoblast cells. It is weak or undetectable in the mesothelial layer.
TS13: trophoblast giant cell Present Non-Uniform 3G A subset of giant cells express at strikingly higher levels.
TS13: ectoplacental cone Present 3G
TS13: spongiotrophoblast Present 3G
TS13: allantois Absent 3G
Specimen not shown: embryonic day 11.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6+ (more )
Note: Fixed in 4% paraformaldehyde, 0.02% glutaraldehyde.
Structure Level Pattern Image Note
TS19: labyrinthine zone Present Regionally restricted After chorioallantoic fusion, expression in the trophoblast component of the labyrinth.
Specimen 5E +/+: embryonic day 8.5 (more )
Note: Fixed in 4% paraformaldehyde, 0.02% glutaraldehyde.
Structure Level Pattern Image Note
TS13: trophoblast giant cell Present 5E left Expression in giant cells.
Specimen 5E -/-: embryonic day 8.5; Dnajb6Gt(ROSABetageo)6AD1Jcc/Dnajb6Gt(ROSABetageo)6AD1Jcc (more )
Note: Fixed in 4% paraformaldehyde, 0.02% glutaraldehyde.
Structure Level Pattern Image Note
TS13: trophectoderm Absent 5E right No expression above background in trophoblast cells of three homozygous mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory