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Gene Expression Data
Assay Details
Assay
Reference: J:31831 Blumenfeld M, et al., Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse. Development. 1991 Oct;113(2):589-99
Assay type: RNA in situ
MGI Accession ID: MGI:2150929
Gene symbol: Hnf1a
Gene name: HNF1 homeobox A
Probe: rat HNF1 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1A,B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: liver Present 1B
TS18: extraembryonic component Present Regionally restricted 1B Positive signal detected over visceral endoderm of yolk sac.

Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: liver Present
TS20: gut Present Regionally restricted Labelling in primary intestinal loops.
TS20: extraembryonic component Present Regionally restricted Labelling in yolk sac.

Specimen 2A,B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: liver Present 2A/B
TS24: gut Present Regionally restricted 2A/B Positive cells correspond to epithelial layer of the lumen of the intestine.
TS24: stomach Absent 2A/B
TS24: duodenum Absent 2A/B Proximal duodenum was negative.
TS24: pancreas Absent 2A/B
TS24: renal cortex Present Regionally restricted 2A/B Labelling exclusively cortical, mostly confined to boundary with medulla; mostly associated with collecting tubules; glomeruli and mesenchymal cells were negative.
TS24: maturing glomerular tuft Absent 2A/B
TS24: spleen Weak 2A/B Low amounts of transcript in the spleen.

Specimen 2E,F: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: gut Present Regionally restricted 2E/F Positive cells correspond to epithelial layer of the lumen of the intestine.

Specimen not shown: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: brain Absent No positive signal was observed in any other tissues examined, including brain.

Specimen not shown: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: embryo Present Regionally restricted Authors state that patterns of hybridization were similar to that seen at other stages.
TS25: thymus Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory