Gene Expression Data
Assay Details
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Assay
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Reference:
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J:64588
Toresson H, et al., Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:2150336
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Antibody:
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Anti-Isl1/2
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Detection system:
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Secondary antibody
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Results
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Specimen
4C:
embryonic day 16.5
(more  )
Specimen
4C:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: corpus striatum |
Present |
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4C
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Expression in the striatal complex (including dorsal striatum, nucleus accumbens and olfactory tubercle).
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Specimen
4D:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: corpus striatum |
Present |
Regionally restricted |
4D
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Expression in the striatal complex reduced compared with wild-type. At rostral levels, olfactory tubercle expression is missing; at caudal levels, reduction in size of expression domain is more apparent.
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Specimen
4E:
embryonic day 16.5
(more )
Specimen
4E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: corpus striatum |
Present |
Regionally restricted |
4E
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Expression in the striatal complex (including dorsal striatum, nucleus accumbens and olfactory tubercle).
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Specimen
4F:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: corpus striatum |
Present |
Regionally restricted |
4F
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Expression in the striatal complex reduced compared with wild-type. At rostral levels, olfactory tubercle expression is missing; at caudal levels, reduction in size of expression domain is more apparent.
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Specimen
8A:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: corpus striatum |
Present |
Regionally restricted |
8A
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Expression in the striatal complex reduced compared with wild-type. At rostral levels, olfactory tubercle expression is missing; at caudal levels, reduction in size of expression domain is more apparent.
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Specimen
8B:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
Pax6Sey/Pax6Sey
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: corpus striatum |
Present |
Regionally restricted |
8B
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Larger domain of expression than in Gsh2 homozygous mutants; expression in the olfactory tubercle.
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Analysis Tools