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Gsx2tm1Ssp
Targeted Allele Detail
Summary
Symbol: Gsx2tm1Ssp
Name: GS homeobox 2; targeted mutation 1, S Steven Potter
MGI ID: MGI:2150162
Synonyms: Gsh-2-
Gene: Gsx2  Location: Chr5:75236262-75238554 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance: Gsx2tm1Ssp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:44324
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced a 487 bp region encoding the last 40 amino acids of the homeodomain and the carboxy terminus. (J:44324)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 187 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gsx2 Mutation:  18 strains or lines available
References
Original:  J:44324 Szucsik JC, et al., Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene. Dev Biol. 1997 Nov 15;191(2):230-42
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory