Otx2 Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:71034 Boyl PP, et al., Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR. Development. 2001 Aug;128(15):2989-3000
Assay type:	Western blot
MGI Accession ID:	MGI:2150151
Gene symbol:	Otx2
Gene name:	orthodenticle homeobox 2

Antibody:

anti-OTX2

Results

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	32 kDa	Genetic Background	Mutant Allele(s)	Sex
wt	E7.5 (a)	TS11: embryo	Present	Not Specified		Not Specified
Otx2 +/-	E7.5 (a)	TS11: embryo	Present (b)	involves: 129P2/OlaHsd * C57BL/6 * DBA/2	Otx2^tm1Pas/Otx2⁺	Not Specified
Otx2 l/l	E7.5 (a)	TS11: embryo	Present (c)	involves: 129P2/OlaHsd * C57BL/6 * DBA/2	Otx2^tm2Asim/Otx2^tm2Asim	Not Specified
Otx2 l/-	E7.5 (a)	TS11: embryo	Present (d)	involves: 129P2/OlaHsd * C57BL/6 * DBA/2	Otx2^tm1Pas/Otx2^tm2Asim	Not Specified

Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Expression levels are half of those seen in wild type.
(c) Expression levels are 40% of those seen in wild type.
(d) Expression levels are 20% of those seen in wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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