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Gene Expression Data
Assay Details
Assay
Reference: J:62941 Malpel S, et al., Regulation of retinoic acid signaling during lung morphogenesis. Development. 2000 Jul;127(14):3057-67
Assay type: RNA in situ
MGI Accession ID: MGI:2150104
Gene symbol: Nr2f2
Gene name: nuclear receptor subfamily 2, group F, member 2
Probe: ARP-1 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5H,5I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trachea epithelium Present 5H Expression in epithelium of trachea (epithelium and mesenchyme) and extrapulmonary airways.
TS19: trachea mesenchyme Present 5H Expression in epithelium of trachea (epithelium and mesenchyme) and extrapulmonary airways.
TS19: respiratory tract Present Regionally restricted 5H Expression in epithelium of trachea (epithelium and mesenchyme) and extrapulmonary airways.
TS19: left lung rudiment mesenchyme Present Regionally restricted 5I Expression in lung mesenchyme at slightly higher levels distally
TS19: right lung rudiment mesenchyme Present Regionally restricted 5I Expression in lung mesenchyme at slightly higher levels distally
TS19: left lung rudiment epithelium Absent 5I No expression in lung epithelium.
TS19: right lung rudiment epithelium Absent 5I No expression in lung epithelium.
Specimen 5J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: left lung mesenchyme Present Uniform 5J Mesenchymal levels markedly increase; distribution is homogeneous.
TS22: right lung mesenchyme Present Uniform 5J Mesenchymal levels markedly increase; distribution is homogeneous.
TS22: main bronchus epithelium Strong 5J Stronger expression in bronchial epithelium.
TS22: left lung epithelium Absent 5J No expression in distal epithelial tubules.
TS22: right lung epithelium Absent 5J No expression in distal epithelial tubules.
Specimen 5K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: left lung mesenchyme Strong Regionally restricted 5K Stronger signals in mesenchyme between buds; less concentrated in subpleural mesenchyme.
TS24: right lung mesenchyme Strong Regionally restricted 5K Stronger signals in mesenchyme between buds; less concentrated in subpleural mesenchyme.
Specimen not shown: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lung Absent No expression in any layer of the lung.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory