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Gene Expression Data
Assay Details
Assay
Reference: J:62024 Cau E, et al., Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium. Development. 2000 Jun;127(11):2323-32
Assay type: RNA in situ
MGI Accession ID: MGI:2149996
Gene symbol: Hes1
Gene name: hes family bHLH transcription factor 1
Probe: Hes1 cDNA5
Probe preparation: Antisense RNA
Results
Specimen 1A +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: olfactory placode Present Graded 1A There is broad expression in the structure. It is highest in the periphery and lower in the central area. Expressing cells are located both apically and basally.
Specimen 1B Mash1-/-: embryonic day 10.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This specimen was flat mounted for microscopic observation.
Structure Level Pattern Image Note
TS17: olfactory placode Present 1B There is broad expression in the structure.
Specimen 1C +/+: embryonic day 10.5 (more )
Note: This specimen was flat mounted for microscopic observation. Double labeled: blue - Hes1; brown - Ascl1 (assay MGI:2150005).
Structure Level Pattern Image Note
TS17: olfactory placode Present 1C The expressing cells are peripheral to the Ascl1+ cells.
Specimen 1G +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: olfactory epithelium Present Regionally restricted 1G Expression is present in most apical cells and absent from the basal cells.
TS20: nasal cavity Present Uniform 1G Expression is present in the mesenchyme surrounding the olfactory epithelium.
Specimen 1H Mash1-/-: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: olfactory epithelium Absent 1H
TS20: nasal cavity Present Uniform 1H Expression is present in the mesenchyme surrounding the olfactory epithelium.
Specimen Not shown +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: olfactory epithelium Weak Single cells Expression is restricted to a few apical cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory